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  • Selemectin is used topically on the skin to treat various parasites, both on and off label. Side effects are rare but may include hair loss at application site, gastrointestinal upset, skin reactions, or neurologic signs. Use with caution in sick or underweight pets, or dogs with the MDR1 mutation. If a negative reaction occurs, please call your veterinary office.

  • Selamectin + sarolaner is used topically on the skin to treat various parasites, both on and off-label, and prevent heartworm in cats. Side effects are rare but may include hair loss at the application site, gastrointestinal upset, skin reactions, or neurologic signs. It should be used with caution in sick or underweight cats. If a negative reaction occurs, please call your veterinary office.

  • Selegiline is typically given by mouth and is used off and on label to treat signs due to cognitive dysfunction syndrome, pituitary dependent Cushing’s disease, anxiety and certain phobias. Side effects may include vomiting, diarrhea, drooling, lack of appetite, and behavioral changes. Do not use in pets that are allergic to it, are aggressive, or in pets receiving other MAOIs, including certain tick collars. If a negative reaction occurs, please call your veterinary office.

  • Several changes occur in the aging cat; they often progress slowly, so it is essential to have your senior cat examined by a veterinarian twice yearly. This is important so that if your cat develops a disease, it can be recognized and treated as early as possible, thereby maintaining her quality of life for as long as possible.

  • Septic arthritis occurs when bacteria or another infectious agent is introduced into one or more joints, leading to painful inflammation. The signs of septic arthritis include heat, swelling, and pain in one or more joints. There is typically decreased range of motion in the affected joint(s), as well as fever, lethargy, and lack of appetite. This handout discusses causes, signs, treatment, and follow-up care.

  • Serotonin is a neurotransmitter produced by the body that regulates mood, sleep, body temperature, pain perception, blood vessel constriction, gastrointestinal function, and even blood clotting. An animal with serotonin syndrome experiences excessive effects of serotonin. This handout reviews the causes, diagnosis and treatment.

  • Sertraline is given by mouth and is used off label to treat behavior disorders in dogs and cats. Common side effects include tiredness, vomiting, diarrhea, lack of appetite, anxiety, irritability, sleeplessness, shaking, tremors, itchy skin, or panting. Do not use in pets that are allergic to it or other SSRIs, or pets that are using MAOIs, flea/tick collars, or cisapride. If a negative reaction occurs, please call your veterinary office.

  • Adrenocorticotropic hormone (ACTH) is produced in the brain and regulates the production of cortisol. When blood cortisol levels are low, it is secreted to stimulate more production, and when blood cortisol levels are high (like from an adrenal tumor), ACTH production is suppressed. ACTH testing alone cannot be used to diagnose Cushing's disease but can help determine what type of Cushing's disease the patient has.

  • Serum biochemistry measures the amount of enzymes, proteins, sugar, electrolytes, minerals, and hormones found in the liquid portion of the blood. Testing for these substances provides information about the body’s organs and tissues, as well as the metabolic state of the animal. This article provides general information on the most routinely measured factors in serum and common reasons for abnormal readings.

  • Electrolytes are the salts and metallic components that are dissolved within the blood serum (serum is the liquid portion of blood). The electrolytes of greatest clinical importance are sodium, potassium, chloride, bicarbonate, phosphorus, and calcium. It is important to detect changes in electrolyte concentrations so that these changes can be treated before the situation becomes severe or life-threatening.